LAURA H. CYPHERS

This JAMA Clinical Guidelines Synopsis summarizes the guideline on antithrombotic therapy for venous thromboembolism from the American College of Chest Physicians.
Source: JAMA Online First

This Viewpoint examines how engaging federally qualified health centers and other outpatient safety-net clinicians and health centers in value-based care can address health disparities faced by patients who have low income or are members of underrepresented racial and ethnic groups.
Source: JAMA Online First

This pragmatic randomized clinical trial compares the efficacy and adverse events of prone positioning in adults not intubated with acute hypoxemia and COVID-19 vs patients receiving usual care without prone positioning.
Source: JAMA Online First

New biological agents, imaging tests, and devices are among the many sectors of technology that have an important role in health care delivery. These technologies vary in the extent to which they aim to replace an existing procedure or medical therapy or provide a new way of treating patients. They also vary widely with regard to their value (ie, incremental clinical benefit and cost) to society. Following approval of the da Vinci Surgical System by the US Food and Drug Administration (FDA) in 2001, robotic surgery has disseminated rapidly across various disciplines and procedures, substituting for conventional (ie, open) or laparoscopic alternatives.
Source: JAMA Online First

This randomized trial assesses the effect of robot-assisted radical cystectomy vs open radical cystectomy on number of days patients were alive and out of the hospital over 90 days following surgery for nonmetastatic bladder cancer.
Source: JAMA Online First

Prior to emergence of the Omicron SARS-CoV-2 variant, and at the time of the issuance of the Emergency Use Authorization (EUA) for the BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine, the efficacy of 2 doses of the 30-µg vaccine in adolescents 12 to 15 years of age and of the 10-µg dose in children 5 to 11 years of age were 100% (95% CI, 75.3%-100%) and 90.7% (95% CI, 67.7%-98.3%), respectively. However, 2 studies published in this issue of JAMA demonstrate that the estimated vaccine effectiveness among children and adolescents with Omicron is considerably lower than in the initial studies, and protection wanes rapidly, especially with the novel SARS-CoV-2 variants.
Source: JAMA Online First

This test-negative, case-control analysis evaluates the association of symptomatic infection with prior vaccination with BNT162b2 to estimate vaccine effectiveness among children and adolescents during Omicron variant predominance.
Source: JAMA Online First

This database study examines vaccination for COVID-19 among children in New York after the emergence of the Omicron variant, including analysis of case rates and hospitalizations for COVID-19 disease.
Source: JAMA Online First

This Viewpoint highlights the risk of burnout and its effects on resident physicians treating patients during the stressful COVID-19 pandemic and summarizes strategies for preventing burnout.
Source: JAMA Online First

This Viewpoint discusses approaches to address clinician occupational well-being based on data and experiences before and during the COVID-19 pandemic.
Source: JAMA Online First