This JAMA Patient Page summarizes the American College of Gastroenterology’s 2021 guidelines on treatment of Clostridioides difficile infection.
Source: JAMA Online First

This Arts and Medicine feature reviews novelist Ludmila Ulitskaya’s Just the Plague, a fictionalization of a historic 1939 plague outbreak in Moscow that has parallels with the 21st-century coronavirus pandemic.
Source: JAMA Online First

This study screens more than 50 000 youths in diverse populations of Colorado and Bavaria to assess whether previous SARS-CoV-2 infection was associated with autoimmunity, which predicts future type 1 diabetes.
Source: JAMA Online First

This Guide to Statistics and Methods provides an overview of regression models for ordinal outcomes, including an explanation of why they are used and their limitations.
Source: JAMA Online First

This Viewpoint summarizes a recent Agency for Healthcare Research and Quality national initiative to improve primary care management of unhealthy alcohol use; discusses how examples from this initiative highlight the discrepancy between electronic health record (EHR) functionality and evidence-based care; and suggests some essential changes that might enable EHRs to better support delivery of behavioral health preventive services.
Source: JAMA Online First

This Medical News article discusses the importance of preventing and surveilling SARS-CoV-2 infections in animals to protect them and avoid viral spillback into human populations.
Source: JAMA Online First

This Viewpoint from US Assistant Secretary for Health Rachel Levine summarizes current understanding of “Long COVID” and addresses the need for agreed-upon terminology, further research and diagnostics, and an effective approach for addressing the long-term effects of COVID-19.
Source: JAMA Online First

This study investigates whether resistance-associated mutations develop after treatment with sotrovimab in high-risk patients infected with the SARS-CoV-2 Omicron variant.
Source: JAMA Online First

This Viewpoint describes 3 learning methods that form the basis of many systems of diagnostic artificial intelligence systems—learning from experts, examples, and experience—and their parallels to clinicians’ existing approaches to learning.
Source: JAMA Online First

This Viewpoint discusses the need for existing quality and reimbursement programs to adjust their data collection and quality measurement to ensure that data reported and reimbursement provided truly reflect the patient population being treated.
Source: JAMA Online First