This Medical News article discusses the first reported instance of polio in the US since 2013.
Source: JAMA Online First

This Medical News article discusses a new technique for wastewater genomic surveillance that could be used to detect emerging viral variants when they first appear in an area.
Source: JAMA Online First

This Medical News feature examines whether the newly authorized Novavax COVID-19 vaccine will spur unvaccinated holdouts to finally get immunized.
Source: JAMA Online First

This cohort study examines the validity of the Kidney Donor Profile Index’s hepatitis C virus (HCV) penalty during the direct-acting antiviral era by comparing 5-year allograft survival between recipients of kidneys from HCV-RNA–positive donors vs HCV-RNA–negative donors.
Source: JAMA Online First

This Viewpoint from FDA Commissioner Robert Califf, MD, emphasizes the agency’s overarching priorities focused on helping to create a system that benefits from abundant high-quality evidence in a transparent environment.
Source: JAMA Online First

This case series describes the clinical resolution of systemic symptoms and lesions, along with any adverse events, in patients with monkeypox infection who were treated with tecovirimat on a compassionate use basis.
Source: JAMA Online First

This JAMA Patient Page describes medication abortion and its risks and effectiveness.
Source: JAMA Online First

This Viewpoint describes the provisions and limitations of prescription drug pricing reforms enacted by US Congress as part of the Inflation Reduction Act in August 2022.
Source: JAMA Online First

An 18-year-old woman had a 14-year history of recurrent skin, nail, and oral mucosal abnormalities, treated with 3- to 6-month courses of itraconazole; the abnormalities typically recurred within 6 to 12 months of discontinuing itraconazole. Skin scrapings from the lower extremities demonstrated fungal elements; fungal culture of the skin scrapings grew Candida albicans. What is the diagnosis and what would you do next?
Source: JAMA Online First

This Viewpoint explores how patient-reported response to treatment informs understanding of clinically meaningful outcomes to help establish patient expectations, inform clinical decision-making, and ensure treatment is sound.
Source: JAMA Online First