LAURA H. CYPHERS

This study uses legislator data from a commercial data service firm database to characterize physicians serving in US federal and state legislatures in 2022 and to compare them with other legislators and with the US physician population.
Source: JAMA Online First

For nearly 50 years, physicians have recognized the close link between ischemic time and myocardial infarct size in patients presenting with ST-segment elevation myocardial infarction (STEMI). Beginning in the 1970s, a series of animal experiments demonstrated the time-dependent nature of this association when investigators temporarily occluded the coronary arteries of dogs and pigs and established the potential for myocardial salvage with rapid coronary reperfusion. These principles were subsequently translated to humans, first with the advent of thrombolytic therapy and then coronary angioplasty. As these therapies became more prevalent, multiple studies demonstrated improved outcomes for STEMI patients who received prompt reperfusion, laying the foundation for the “time is muscle” mantra.
Source: JAMA Online First

This cross-sectional study compares in-hospital mortality among patients with ST-segment elevation myocardial infarction receiving treatment within the US national guidelines–recommended target times vs later.
Source: JAMA Online First

This Viewpoint discusses a federal policy loophole that allows psychotropic cannabis products to be commercially marketed and sold across the US, even in states where recreational cannabis is not legal.
Source: JAMA Online First

This Viewpoint discusses the ways in which the tobacco industry can advance their stated goals of harm reduction and a smoke-free future.
Source: JAMA Online First

The 7-day week, with Sunday as a day of rest, dates back to the Roman Emperor Constantine. For patients with end-stage kidney disease (ESKD) who undergo hemodialysis on a Monday, Wednesday, and Friday schedule, Sunday represents an important respite. Hemodialysis is arduous, and fatigue often persists the day after. Two days after hemodialysis, patients feel better but are due for another session. Many patients undergoing hemodialysis report that Sunday is the only day that they both feel well and do not require hemodialysis. For patients with ESKD who undergo hemodialysis on a Tuesday, Thursday, and Saturday schedule, Monday is their day of rest.
Source: JAMA Online First

This retrospective cohort study assesses whether a longer interval between hemodialysis and subsequent surgery is associated with higher postoperative mortality in patients with end-stage kidney disease treated with hemodialysis.
Source: JAMA Online First

This Medical News article discusses how cardiac xenotransplantation with genetically modified pig hearts might help relieve the shortage of human donor hearts.
Source: JAMA Online First

This study assesses changes in the number of abortions and changes in the percentage of out-of-state abortions among Texas residents performed 12 or more weeks of gestation in the first six 6 months following implementation of a Texas senate bill prohibiting abortions after detection of embryonic cardiac activity.
Source: JAMA Online First

This Viewpoint outlines how the revival of now defunct state-level antisodomy laws would harm the health care of LGBTQ individuals should the US Supreme Court reverse itself and urges medical professionals and their societies to advocate for the immediate abolition of antisodomy laws.
Source: JAMA Online First