This Viewpoint discusses a proposed DHHS rule to address discrimination in clinical algorithms and the need for additional considerations to ensure the burden of liability for biased algorithms is not disproportionately placed on health care professionals.
Source: JAMA Online First

This Viewpoint discusses recent legal directives by the DHHS and FDA that could increase health care entities’ liability for possible discriminatory biases of clinical algorithms and the need for additional legal clarity to avoid adverse effects on algorithm development and use.
Source: JAMA Online First

This Medical News article discusses a recent study that investigated the benefits of brief bursts of intense physical activity during daily life.
Source: JAMA Online First

This Viewpoint from leadership at the US Food and Drug Administration (FDA) proposes the creation of a comprehensive “care package” framework of resources to help maximize cessation of tobacco use, including components focused on strategies at the individual, health system, and population levels.
Source: JAMA Online First

This Medical News feature examines the relatively newly identified fungus Candida auris, a hardy species that can resist treatment with antifungal agents, is highly contagious, and is associated with serious infections and significant mortality.
Source: JAMA Online First

This matched-cohort study uses data from the French National Health Insurance database to assess whether a 19.5-mg levonorgestrel intrauterine system, vs a 52-mg system, is associated with increased use of antidepressant, hypnotic, and anxiolytic medications.
Source: JAMA Online First

In this narrative medicine essay, a psychiatrist finds that the difficulties she had helping her parents obtain Paxlovid seemed a common experience among her colleagues, so she offers patients and the medical community suggestions on how to simplify the process.
Source: JAMA Online First

This Medical News article discusses the 2022 Clinical Practice Guideline for Prescribing Opioids for Pain, an update to widely criticized recommendations released by the CDC in 2016.
Source: JAMA Online First

A 62-year-old nulligravida woman had 10 months of progressive abdominal distension, diffuse abdominal pain, and 25-kg weight gain. She had no nausea or vomiting, hematochezia, or stool changes; pelvic and abdominal examination showed a large abdominal mass extending from the epigastrium to the pelvis but no other abnormalities; results of laboratory testing, including cancer antigen levels, were unremarkable. What is the diagnosis and what would you do next?
Source: JAMA Online First

This Viewpoint examines the first 50 years of the US End-Stage Renal Disease (ESRD) program, including technological updates and continuing challenges to update cost and quality.
Source: JAMA Online First