Type 1 diabetes is a common autoimmune disease in which progressive loss of pancreatic beta cells results in lifelong dependence on insulin. Despite rapid advances in the technology for insulin delivery and glucose monitoring, it remains challenging for patients to reach optimal glycemic control to prevent the serious long-term complications associated with type 1 diabetes. Even modest amounts of endogenous insulin production provide substantial benefits by improving glycemic control and reducing the risk of hypoglycemia and vascular complications. Effective interventions that preserve beta cell function both before and after the diagnosis of type 1 diabetes are therefore enormously welcome.
Source: JAMA Online First
This randomized clinical trial compares the efficacy of intensive glucose management, which included use of an automated insulin delivery system, vs standard care, which included use of a continuous glucose monitor, to achieve near normalization of glucose levels to preserve pancreatic β cell function in youths with newly diagnosed type 1 diabetes.
Source: JAMA Online First
This randomized clinical trial compares the effect of verapamil on pancreatic beta cell function vs placebo in children and adolescents with newly diagnosed type 1 diabetes.
Source: JAMA Online First
This Medical News article discusses US initiatives to improve health care worker well-being as burnout and intent to leave to medicine reach record levels.
Source: JAMA Online First
In this narrative medicine essay, a physician recounts her family’s experience with critical illness and death and how she came to appreciate both the health care team’s perspective and the family’s perspective regarding when to have hope and when to let go.
Source: JAMA Online First
This Viewpoint discusses the need for public funding for research that supports health workforce well-being and addresses occupational burnout among health care practitioners.
Source: JAMA Online First
This Viewpoint highlights the increasing levels of burnout among physicians, discusses how burnout can erode professionalism, and suggests possible steps physicians and health care organizations might take to lessen burnout and maintain professionalism in the setting of burnout.
Source: JAMA Online First
This Viewpoint discusses the need for clinicians to be involved in every stage of the development of patient safety interventions in order to not only improve patient care, but also maximize the interventions’ effectiveness and ensure clinician well-being and buy-in.
Source: JAMA Online First
When US adults reached age 65 years and became eligible for Medicare, their visits for restorative dental procedures such as fillings or crowns fell by 8.7%, according to survey responses from 97 108 participants aged 50 to 85 years. Moreover, the loss of all teeth, or complete edentulism, increased by 4.8% at age 65 years. In addition, enrollment in Medicare Advantage, which often offers dental coverage, was not tied to increased use of dental services compared with enrollment in traditional Medicare.
Source: JAMA Online First
The antiseizure drug valproic acid might improve heart function in transplant recipients and expand the pool of donor hearts by increasing their storage time, a preclinical study published in Science Translational Medicine suggests.
Source: JAMA Online First