This study evaluates whether patients enrolled in trials of aducanumab, EMERGE and ENGAGE, were representative of patients with dementia enrolled in Medicare by estimating the proportions of Medicare beneficiaries with Alzheimer disease (AD) or mild cognitive impairment (MCI) who would have been excluded from these trials.
Source: JAMA Online First

This Viewpoint reviews the World Trade Center Health Program, established in 2011 to fund health care for responders and survivors of the 9/11 attacks in the US, including covered conditions and changing factors such as an aging member population.
Source: JAMA Online First

This Research Letter presents findings from case-control surveillance of COVID-19 vaccination during pregnancy and spontaneous abortion.
Source: JAMA Online First

This Medical News article discusses farmworkers’ heat-related health risks and efforts to establish a national standard to help protect them from dangerous working conditions.
Source: JAMA Online First

Vaccines represent one of the greatest public health achievements of modern medicine. They must pass rigorous and predetermined efficacy and safety metrics prior to licensure. Additionally, postmarketing safety surveillance is essential to detect rare or severe vaccine-associated adverse events, particularly because of the large numbers of individuals exposed.
Source: JAMA Online First

This study reports an interim analysis of safety surveillance data of 23 serious outcomes following vaccination with 1 of the mRNA COVID-19 vaccines based on comprehensive health records from a large US population.
Source: JAMA Online First

This Medical News article discusses ongoing physical and mental health effects for emergency personnel, recovery and cleanup workers, and volunteers who responded on and after the September 11, 2001, terrorist attacks.
Source: JAMA Online First

This study examines the prevalence of SARS-CoV-2 antibodies among blood donors aged 16 to 64 years in Kenya from January to March 2021.
Source: JAMA Online First

This study estimates trends in SARS-CoV-2 seroprevalence related to infection and vaccination in the US population.
Source: JAMA Online First

This technical brief to support the US Preventive Services Task Force (USPSTF) describes current research on screening and interventions for social risk factors such as food insecurity, financial strain, and housing instability to inform USPSTF considerations of the implications for its portfolio of recommendations.
Source: JAMA Online First