The 7-day week, with Sunday as a day of rest, dates back to the Roman Emperor Constantine. For patients with end-stage kidney disease (ESKD) who undergo hemodialysis on a Monday, Wednesday, and Friday schedule, Sunday represents an important respite. Hemodialysis is arduous, and fatigue often persists the day after. Two days after hemodialysis, patients feel better but are due for another session. Many patients undergoing hemodialysis report that Sunday is the only day that they both feel well and do not require hemodialysis. For patients with ESKD who undergo hemodialysis on a Tuesday, Thursday, and Saturday schedule, Monday is their day of rest.
Source: JAMA Online First